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Suture of the Ovary After Enucleation of Ovarian Endometrioma
Sponsor: Università degli Studi dell'Insubria
Summary
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity. According to the most updated guidelines of the European Society of Human Reproduction and Embryology (ESHRE), infertile women with endometriomas smaller than 3 cm should be addressed directly to Assisted Reproduction Technology (ART); conversely, for infertile women with endometriomas larger than 3 cm, enucleation of ovarian endometriomas could be considered in order to improve reproductive outcomes (both spontaneous and ART pregnancy rate). To date, literature data do not allow to draw a firm conclusion about the best strategy to reduce ovarian damage during enucleation of ovarian endometriomas: in particular, investigators still lack robust evidence in order to choose between suturing the ovary or not after the enucleation. In this scenario, the aim of our the study will be to compare functional outcomes of the ovary in a group of women undergoing suturing of the ovarian cortex after laparoscopic enucleation of endometriomas (cases) and a group of women undergoing laparoscopic enucleation of endometriomas without subsequent suture of the ovarian cortex.
Official title: Comparison Between Suture of the Ovary Versus no Suture After Enucleation of Ovarian Endometrioma
Key Details
Gender
FEMALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-05
Completion Date
2027-05
Last Updated
2021-04-29
Healthy Volunteers
No
Conditions
Interventions
Suture of the ovarian cortex
Suture of the ovarian cortex after laparoscopic enucleation of endometriomas, using one single monofilament suture material, continuous suture technique with maximum 5 transfixion of the ovarian cortex and intracorporeal knots only (no extracorporeal knots).
No suture of the ovarian cortex
Laparoscopic enucleation of endometriomas without suture of the ovarian cortex
Locations (1)
"Filippo Del Ponte" Hospital
Varese, Italy