Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
NOT YET RECRUITING
NCT03788720
NA

Suture of the Ovary After Enucleation of Ovarian Endometrioma

Sponsor: Università degli Studi dell'Insubria

View on ClinicalTrials.gov

Summary

Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity. According to the most updated guidelines of the European Society of Human Reproduction and Embryology (ESHRE), infertile women with endometriomas smaller than 3 cm should be addressed directly to Assisted Reproduction Technology (ART); conversely, for infertile women with endometriomas larger than 3 cm, enucleation of ovarian endometriomas could be considered in order to improve reproductive outcomes (both spontaneous and ART pregnancy rate). To date, literature data do not allow to draw a firm conclusion about the best strategy to reduce ovarian damage during enucleation of ovarian endometriomas: in particular, investigators still lack robust evidence in order to choose between suturing the ovary or not after the enucleation. In this scenario, the aim of our the study will be to compare functional outcomes of the ovary in a group of women undergoing suturing of the ovarian cortex after laparoscopic enucleation of endometriomas (cases) and a group of women undergoing laparoscopic enucleation of endometriomas without subsequent suture of the ovarian cortex.

Official title: Comparison Between Suture of the Ovary Versus no Suture After Enucleation of Ovarian Endometrioma

Key Details

Gender

FEMALE

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2023-05

Completion Date

2027-05

Last Updated

2021-04-29

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Suture of the ovarian cortex

Suture of the ovarian cortex after laparoscopic enucleation of endometriomas, using one single monofilament suture material, continuous suture technique with maximum 5 transfixion of the ovarian cortex and intracorporeal knots only (no extracorporeal knots).

PROCEDURE

No suture of the ovarian cortex

Laparoscopic enucleation of endometriomas without suture of the ovarian cortex

Locations (1)

"Filippo Del Ponte" Hospital

Varese, Italy