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SAPT Versus DAPT in Incomplete Revascularization After CABG
Sponsor: Campus Bio-Medico University
Summary
The study aims to compare the efficacy of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients with incomplete revascularization after coronary artery bypass graft surgery (CABG). Before hospital discharge, patients will be 1:1 randomized to SAPT (acetylsalicylic acid 100 mg/die) or DAPT (acetylsalicylic acid 100 mg/die + ticagrelor 90 mg bis in die). DAPT will be continued for 12 months, and ticagrelor will be withdrawn thereafter. Primary endpoint is the evaluation of cardiac-related mortality at 5 years from hospital discharge.
Official title: Single Versus Dual Antiplatelet Therapy in Patients With Incomplete Revascularization After Coronary Artery Bypass Graft Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
800
Start Date
2019-01-02
Completion Date
2026-12-31
Last Updated
2022-07-21
Healthy Volunteers
No
Conditions
Interventions
Ticagrelor
90 mg bis in die
acetylsalicylic acid
100 mg die
Locations (1)
Università Campus Bio-Medico di Roma
Rome, Italy