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RECRUITING
NCT03792919
PHASE4

Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)

Sponsor: Humanity & Health Medical Group Limited

View on ClinicalTrials.gov

Summary

To Identify the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance among chronic hepatitis B(CHB) patients.

Official title: Virological Response After Cessation of Long Term Anti-HBV Nucleos(t)Ide Analogues (NAs) vs. Keeping on NAs Among Chronic Hepatitis B (CHB) Patients

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

2000

Start Date

2018-12-01

Completion Date

2025-12-31

Last Updated

2025-03-24

Healthy Volunteers

No

Interventions

DRUG

Stop current treatment (anti-HBV neucleos(t)ides)

Stop the current anti-HBV neucleos(t)ides treatment among the CHB patients who meet the criteria the stopping rule of long term treatment.

DRUG

Keep current treatment (anti-HBV neucleos(t)ides)

Keep the current anti-HBV neucleos(t)ides treatment among the CHB patients who meet the criteria the stopping rule of long term treatment.

Locations (1)

Humanity & Health Research Centre

Hong Kong, Hong Kong SAR, Hong Kong