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COMPLETED
NCT03805607
PHASE4

IV Ketorolac on Platelet Function Post-Cesarean Delivery

Sponsor: Beth Israel Deaconess Medical Center

View on ClinicalTrials.gov

Summary

Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers results in inhibition of platelet aggregation and prolonged bleeding time. However, in the obstetric population, the presence and degree of platelet inhibition after NSAID exposure is less clear. The investigators plan to use Platelet Aggregometry and Thromboelastography (TEG) to evaluate the effect of ketorolac on platelets.

Official title: Prospective Evaluation of the Effects of IV Ketorolac on Platelet Function Post-Cesarean Delivery

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2021-01-18

Completion Date

2024-03-30

Last Updated

2026-05-29

Healthy Volunteers

Yes

Interventions

DRUG

Ketorolac Tromethamine 30 MG/ML

Ketorolac 30 mg

DRUG

Placebos

Normal Saline

Locations (1)

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States