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IV Ketorolac on Platelet Function Post-Cesarean Delivery
Sponsor: Beth Israel Deaconess Medical Center
Summary
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers results in inhibition of platelet aggregation and prolonged bleeding time. However, in the obstetric population, the presence and degree of platelet inhibition after NSAID exposure is less clear. The investigators plan to use Platelet Aggregometry and Thromboelastography (TEG) to evaluate the effect of ketorolac on platelets.
Official title: Prospective Evaluation of the Effects of IV Ketorolac on Platelet Function Post-Cesarean Delivery
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2021-01-18
Completion Date
2024-03-30
Last Updated
2026-05-29
Healthy Volunteers
Yes
Conditions
Interventions
Ketorolac Tromethamine 30 MG/ML
Ketorolac 30 mg
Placebos
Normal Saline
Locations (1)
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States