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ACTIVE NOT RECRUITING
NCT03807414

Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients

Sponsor: Careggi Hospital

View on ClinicalTrials.gov

Summary

The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting. Nonetheless, most of the clinical trials aimed at exploring the effect of EBPT on patients' long-term outcomes have failed to demonstrate consistent results regarding 28 day- or hospital- mortality rates. The aim of this observational prospective registry is to evaluate if there is a cluster of critically ill patients that mostly benefits from extracorporeal blood purification therapies with oXiris membrane.

Official title: Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for Extracorporeal Blood Purification Therapies in Critically Ill Patients

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

270

Start Date

2019-06-28

Completion Date

2025-09-30

Last Updated

2025-02-12

Healthy Volunteers

No

Interventions

DEVICE

oXiris

Every center will prescribe EBPT with oXiris in accordance with local practice and local levels of expertise. No variation in treatment prescription and/or treatment solutions will derive from participation in this prospective observational study. Nonetheless, every setting parameter will be recorded in the web-based registry and analyzed a-posteriori to reveal a potential correlation with the patient outcomes.

Locations (12)

Presidio Ospedaliero di Esine

Esine, Brescia, Italy

S. Giuseppe Hospital

Empoli, Firenze, Italy

IRCCS Policlinico S. Donato Milanese

San Donato Milanese, Milano, Italy

Ospedale Sacro Cuore di Gesù-Fatebenefratelli

Benevento, Italy

Azienda Ospedaliero Universitaria Careggi

Florence, Italy

A.O.U. della Campania "L. Vanvitelli"

Naples, Italy

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy

Ospedale S. Maria della Misericordia

Perugia, Italy

Ospedale San Jacopo

Pistoia, Italy

S.Camillo Forlanini Hospital

Roma, Italy

Cristo Re Hospital

Roma, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Roma, Italy