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Obesity and Endogenous Oxalate Synthesis
Sponsor: University of Alabama at Birmingham
Summary
The goal of this study is to determine if obesity is associated with increased endogenous oxalate synthesis as assessed by urinary oxalate excretion, which is a known risk factor for calcium oxalate kidney stones. The study will recruit adult participants without history of kidney stones. Participants will * Ingest fixed diets containing low amounts of oxalate for 4 days * Collect 24-hr urine samples during the fixed diet
Key Details
Gender
All
Age Range
19 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
58
Start Date
2013-01-01
Completion Date
2024-07-31
Last Updated
2026-09-21
Healthy Volunteers
Yes
Conditions
Interventions
Normal Individuals
Controlled Dietary phase: Low oxalate fixed diet 4 days of fixed normal calorie diet with low oxalate (\< 60 mg/day), normal calcium (800-1200 mg/day)
Locations (1)
University of Alabama at Birmingham
Birmingham, Alabama, United States