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Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
Sponsor: Technical University of Munich
Summary
In this mono-center pilot trial, surgical patients who are at high risk to be admitted to intensive care will be screened and asked for participation. We are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.
Official title: Metabolomics Pilot Study on Postoperative Intensive Care Acquired Muscle Weakness (MIRACLE-I Study)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2022-09-02
Completion Date
2026-12-31
Last Updated
2026-03-03
Healthy Volunteers
Not specified
Conditions
Locations (3)
Medical University of Vienna
Vienna, Vienna, Austria
Klinikum rechts der Isar, School of Medicine, Technical University of Munich
Munich, Bavaria, Germany
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, Germany