Clinical Research Directory
Browse clinical research sites, groups, and studies.
Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women
Sponsor: BC Centre for Improved Cardiovascular Health
Summary
The project is focussed on evaluating the impact of using a female-specific threshold in the diagnosis of myocardial infarction. This female threshold is lower than the overall hs-cTn threshold currently in use. The investigators hypothesize that this change in process, applied at the hospital level, will lead to better assessment, treatment and outcomes of women presenting to the emergency department with chest pain that is cardiac in nature.
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24000
Start Date
2020-02-08
Completion Date
2025-03-31
Last Updated
2024-10-09
Healthy Volunteers
No
Interventions
Introduction of a lower female hs-cTn threshold
The new female hs-cTn threshold will be baed on current recommendations for each of the assays used (hs-cTn T and I). The hospitals are the unit of randomization. At 5-month intervals, randomly selected hospitals will be advised that they are to transition to the intervention phase. For all men, the standard of care, overall population threshold will be used throughout the entire study.
Locations (1)
St. Paul's Hospital
Vancouver, British Columbia, Canada