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COMPLETED
NCT03825523
NA

Immediate ART in Subjects With Opportunistic Diseases

Sponsor: Gustavo Reyes-Teran

View on ClinicalTrials.gov

Summary

The aim of this study is to compare the clinical response and mortality rate due to opportunistic disease in HIV-infected individuals who start immediate versus conventional antiretroviral therapy (ART). Immediate ART (iART) is defined as starting antiretroviral therapy within the first 48 hours after hospitalization. Conventional ART (cART) is defined as starting antiretroviral therapy once the opportunistic infection is under control at the discretion of the infectious disease specialist.

Official title: Impact of the Timing of Antiretroviral Therapy Initiation (Immediate Versus Early) on the Mortality Rate of HIV/AIDS Patients Hospitalized With an Opportunistic Disease

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

114

Start Date

2018-01-29

Completion Date

2025-08-05

Last Updated

2026-06-30

Healthy Volunteers

No

Interventions

DRUG

Antiretroviral Therapy (ART)

Immediate initiation of ART within 48 hours of hospital admission.

DRUG

Antiretroviral Therapy (ART)

Deferred initiation of ART, with timing determined by the treating physician based on clinical stability and control of the opportunistic infection.

Locations (1)

Centro de Investigacion en Enfermedades Infecciosas

México, State of Mexico, Mexico