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Sex Differences in the Response to Abstinence From Alcohol.
Sponsor: Indiana University
Summary
In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the present study, the investigators propose to study how men and women respond to abstinence, and whether this information can be used to improve intervention and prevention strategies.
Key Details
Gender
All
Age Range
21 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2019-04-10
Completion Date
2026-08-31
Last Updated
2025-12-18
Healthy Volunteers
Yes
Conditions
Interventions
Abstinence from alcohol
Participants will undergo a laboratory alcohol infusion session that terminates 2 weeks of monitored abstinence from alcohol
Usual drinking
Participants will undergo a laboratory alcohol infusion session during a period of usual drinking behavior
Intravenous Alcohol
During the laboratory alcohol infusion sessions, alcohol is infused through an indwelling catheter.
Locations (1)
University Hospital
Indianapolis, Indiana, United States