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RECRUITING
NCT03827460
PHASE1

Sex Differences in the Response to Abstinence From Alcohol.

Sponsor: Indiana University

View on ClinicalTrials.gov

Summary

In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the present study, the investigators propose to study how men and women respond to abstinence, and whether this information can be used to improve intervention and prevention strategies.

Key Details

Gender

All

Age Range

21 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2019-04-10

Completion Date

2026-08-31

Last Updated

2025-12-18

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Abstinence from alcohol

Participants will undergo a laboratory alcohol infusion session that terminates 2 weeks of monitored abstinence from alcohol

BEHAVIORAL

Usual drinking

Participants will undergo a laboratory alcohol infusion session during a period of usual drinking behavior

DRUG

Intravenous Alcohol

During the laboratory alcohol infusion sessions, alcohol is infused through an indwelling catheter.

Locations (1)

University Hospital

Indianapolis, Indiana, United States