Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT03827616
NA

Moderately Hypofractionated Radiotherapy for Prostate Cancer.

Sponsor: Tatarstan Cancer Center

View on ClinicalTrials.gov

Summary

Radiation therapy is one of the standard treatments for men with prostate cancer. Moderately hypofractionated radiotherapy has been established to be equivalent to standard fractionated radiotherapy in several large randomized clinical trials, however different hypofractionated regimens have been used in these studies. The two most common hypofractionated regimens are 70 Gy in 28 fractions and 60 Gy in 20 fractions, both are considered standard of care, however it is not unknown which regimen is better in terms of effectiveness and toxicity. The aim of this randomized controlled clinical trial is to compare the two hypofractionated radiotherapy regimens using Helical Tomotherapy.

Official title: A Prospective Randomized Phase II Clinical Trial of Moderately Hypofractionated Radiotherapy (70 Gy in 28 Fractions vs 60 Gy in 20 Fractions) Using Helical Tomotherapy.

Key Details

Gender

MALE

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2019-01-25

Completion Date

2030-02-01

Last Updated

2026-04-08

Healthy Volunteers

No

Interventions

RADIATION

Hypofractionated IMRT using helical Tomotherapy.

70 Gy in 28 fractions intensity-modulated radiotherapy (IMRT)

RADIATION

Hypofractionated IMRT using helical Tomotherapy.

60 Gy in 20 fractions intensity-modulated radiotherapy (IMRT) using helical Tomotherapy.

Locations (1)

Tatarstan Cancer Cente

Kazan', Tatarstan Republic, Russia