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Targeted Potassium Levels for Prevention of ICD Therapy
Sponsor: Rigshospitalet, Denmark
Summary
This study evaluates whether a rigorously controlled high-normal level of serum-potassium (4.5-5.0 mEq/L) using dietary recommendations, potassium supplements and mineralocorticoid receptor antagonists will results in a lower incidence of cardiac arrhythmias in patients with an ICD. Patients will be randomized to this treatment or a control arm, where patients will receive usual guideline recommended follow-up.
Official title: Arrhythmia Prevention in High Risk Cardiovascular Patients Using Targeted Potassium Levels
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1200
Start Date
2019-03-01
Completion Date
2035-04-01
Last Updated
2025-05-09
Healthy Volunteers
No
Conditions
Interventions
Targeted serum potassium level
In the following order, following advices end prescriptions will be provided: 1) Potassium rich dietary advice, 2) Mineralocorticoid receptor antagonists, 3) Potassium supplementation,
Locations (3)
Gentofte University Hospital
Gentofte Municipality, Hellerup, Denmark
Roskilde University Hospital
Roskilde, Region Sjælland, Denmark
Rigshospitalet
Copenhagen, Denmark