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WITHDRAWN
NCT03833401
NA

Dental Pulp Regeneration by Autologous Tissue Transplantation

Sponsor: University of California, Los Angeles

View on ClinicalTrials.gov

Summary

The purpose of this study is to develop new improved therapy for teeth that require root canals due to tooth infection or tooth inflammation. Investigators will recruit total of 50 participants from the age group 7 - 50 at the UCLA School of Dentistry Endodontic clinic. The participants will be divided into two groups, one will receive traditional therapy, which may include root canal or a procedure called "revascularization," which is a procedure trying to regrow the tissue inside the tooth. The other group of participants will receive the test treatment, which will involve harvesting of pulp tissues from the same tooth or other teeth that are planned for extraction. Investigators will prepare these tissues and place the tissues back into the cleaned root canal space with induced bleeding to allow regrowth of the tissue. For all participants, investigators will follow up after 6, 12, and 24 months in a shorter appointment, which may involve taking x-ray and clinical exam.

Official title: Dental Pulp Regeneration for Root Canals by Autologous Tissue Transplantation

Key Details

Gender

All

Age Range

7 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

0

Start Date

2019-02-14

Completion Date

2021-06-30

Last Updated

2026-07-23

Healthy Volunteers

Yes

Interventions

PROCEDURE

Autologous tissue transplantation

Root canal disinfection and revascularization with patient's own minced pulp tissues

PROCEDURE

Root canal revascularization

Root canal disinfection and revascularization without tissue transplantation

Locations (1)

UCLA School of Dentistry

Los Angeles, California, United States