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Dental Pulp Regeneration by Autologous Tissue Transplantation
Sponsor: University of California, Los Angeles
Summary
The purpose of this study is to develop new improved therapy for teeth that require root canals due to tooth infection or tooth inflammation. Investigators will recruit total of 50 participants from the age group 7 - 50 at the UCLA School of Dentistry Endodontic clinic. The participants will be divided into two groups, one will receive traditional therapy, which may include root canal or a procedure called "revascularization," which is a procedure trying to regrow the tissue inside the tooth. The other group of participants will receive the test treatment, which will involve harvesting of pulp tissues from the same tooth or other teeth that are planned for extraction. Investigators will prepare these tissues and place the tissues back into the cleaned root canal space with induced bleeding to allow regrowth of the tissue. For all participants, investigators will follow up after 6, 12, and 24 months in a shorter appointment, which may involve taking x-ray and clinical exam.
Official title: Dental Pulp Regeneration for Root Canals by Autologous Tissue Transplantation
Key Details
Gender
All
Age Range
7 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
0
Start Date
2019-02-14
Completion Date
2021-06-30
Last Updated
2026-07-23
Healthy Volunteers
Yes
Conditions
Interventions
Autologous tissue transplantation
Root canal disinfection and revascularization with patient's own minced pulp tissues
Root canal revascularization
Root canal disinfection and revascularization without tissue transplantation
Locations (1)
UCLA School of Dentistry
Los Angeles, California, United States