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RECRUITING
NCT03836950
PHASE1/PHASE2

rTMS to Improve Cognition in Parkinson's

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical parkinsonism and mild impairments in their thinking. The hypothesis is that rTMS can improve thinking for people with Parkinson's disease or atypical parkinsonism who are experiencing mild problems with their thinking ability.

Official title: rTMS as a Cognitive Rehabilitation Approach in Veterans With Parkinson's Disease

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

56

Start Date

2020-04-01

Completion Date

2028-03-30

Last Updated

2026-04-08

Healthy Volunteers

No

Interventions

DEVICE

MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)

The coil will be held tangentially to the skull at approximately 45º from the midline. One rTMS session will consist of 40 trains of 5sec each at 110% of resting motor threshold and 15Hz will be provided at the left DLPFC.

DEVICE

MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)

The coil will be held tangentially to the skull at approximately 45º from the midline. The sham coil will not release any stimulation, but it will look, feel and sound like the real rTMS

Locations (2)

Jesse Brown VA Medical Center, Chicago, IL

Chicago, Illinois, United States

Edward Hines Jr. VA Hospital, Hines, IL

Hines, Illinois, United States