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rTMS to Improve Cognition in Parkinson's
Sponsor: VA Office of Research and Development
Summary
The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical parkinsonism and mild impairments in their thinking. The hypothesis is that rTMS can improve thinking for people with Parkinson's disease or atypical parkinsonism who are experiencing mild problems with their thinking ability.
Official title: rTMS as a Cognitive Rehabilitation Approach in Veterans With Parkinson's Disease
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2020-04-01
Completion Date
2028-03-30
Last Updated
2026-04-08
Healthy Volunteers
No
Interventions
MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
The coil will be held tangentially to the skull at approximately 45º from the midline. One rTMS session will consist of 40 trains of 5sec each at 110% of resting motor threshold and 15Hz will be provided at the left DLPFC.
MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
The coil will be held tangentially to the skull at approximately 45º from the midline. The sham coil will not release any stimulation, but it will look, feel and sound like the real rTMS
Locations (2)
Jesse Brown VA Medical Center, Chicago, IL
Chicago, Illinois, United States
Edward Hines Jr. VA Hospital, Hines, IL
Hines, Illinois, United States