Clinical Research Directory

Inclusion Criteria: * Patients with severe symptomatic aortic stenosis who it was accepted to be treated with TAVI by a multidisciplinary team "Heat Team". * TAVI was successfully implanted (according to Valve Academic Research Consortium II criteria) and are under treatment with double antiplatelet therapy. * Signed informed consent to participate in this study. Exclusion Criteria: * Age under 18 years and pregnant or of childbearing age. * Acute Recent stroke recent \<14 days before TAVI. * The patients with proven allergy to aspirin, clopidogrel * Patients that after TAVI cannot undergo a double antiplatelet regimen for 6 months due to a new post-TAVI medical indication or are anticoagulated. * Knowledge of pregnancy or lactation Thrombocytopenia (\<50,000 platelets U / L) well documented and clinically relevant. * The patients with documented moderate or severe hepatic insufficiency * Severe chronic renal insufficiency with creatinine clearance \<30 ml / min. * The patients who can not attend the follow-up visits scheduled in the study