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RECRUITING
NCT03848312
PHASE3

Preventing Alzheimer's With Cognitive Training

Sponsor: University of South Florida

View on ClinicalTrials.gov

Summary

Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residential care needs) and indirect (e.g., lost productivity of family caregivers) economic costs. Implementing interventions to prevent MCI and dementia among older adults is of critical importance to health and maintained quality-of-life for millions of Americans. Recent data analyses from the Advanced Cognitive Training in Vital Elderly study (ACTIVE) indicate that a specific cognitive intervention, speed of processing training (SPT), significantly delays the incidence of cognitive impairment across 10 years. The primary contribution of the proposed research will be the determination of whether this cognitive training technique successfully delays the onset of clinically defined MCI or dementia across three years.

Official title: Cognitive Training to Reduce Incidence of Cognitive Impairment in Older Adults

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

7600

Start Date

2019-02-19

Completion Date

2026-01-31

Last Updated

2024-09-26

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Cognitive Training

Participants will be completing a total of 45 computerized sessions.

BEHAVIORAL

Computerized Cognitive Stimulation

Participants will be completing a total of 45 computerized cognitive stimulation sessions.

Locations (7)

University of Florida

Gainesville, Florida, United States

University of Florida

Jacksonville, Florida, United States

University of North Florida

Jacksonville, Florida, United States

The Roskamp Institute

Sarasota, Florida, United States

University of South Florida

Tampa, Florida, United States

Duke Health

Durham, North Carolina, United States

Clemson University Institute for Engaged Aging

Seneca, South Carolina, United States