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Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota
Sponsor: University of Stellenbosch
Summary
This will be the first study to evaluate the use of Nyaditum resae® as a potential agent for reducing antibiotic-associated gut dysbiosis in patients with drug-susceptible TB, and potentially improving clinical and microbiological markers of outcome
Official title: Nyaditum Resae® (a Food Supplement) as a Co-adjuvant During First-line Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota - a Pilot Double-blind Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2019-05-10
Completion Date
2025-12-31
Last Updated
2025-05-16
Healthy Volunteers
No
Conditions
Interventions
Nyaditum resae®
Heat-killed Mycobacterium manresensis
Mannitol
Placebo
Locations (2)
Scottsdene Clinic
Cape Town, Western Cape, South Africa
Wallacedene Clinic
Cape Town, Western Cape, South Africa