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ACTIVE NOT RECRUITING
NCT03851159
NA

Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota

Sponsor: University of Stellenbosch

View on ClinicalTrials.gov

Summary

This will be the first study to evaluate the use of Nyaditum resae® as a potential agent for reducing antibiotic-associated gut dysbiosis in patients with drug-susceptible TB, and potentially improving clinical and microbiological markers of outcome

Official title: Nyaditum Resae® (a Food Supplement) as a Co-adjuvant During First-line Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota - a Pilot Double-blind Randomised Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2019-05-10

Completion Date

2025-12-31

Last Updated

2025-05-16

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Nyaditum resae®

Heat-killed Mycobacterium manresensis

OTHER

Mannitol

Placebo

Locations (2)

Scottsdene Clinic

Cape Town, Western Cape, South Africa

Wallacedene Clinic

Cape Town, Western Cape, South Africa