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Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)
Sponsor: Helsinki University Central Hospital
Summary
Remote ischemic preconditioning (RIPC) is a concept where remotely induced ischemia produces protection against ischemia-reperfusion injury in a remote organ. RIPC has been studied extensively in animal models and heart surgery, but it's benefit in transplantation has been studied less. The primary aim of this study is to find out whether RIPC performed in a donor in donation after brain-death (DBD) could improve delayed graft function rate of kidney transplants.
Official title: Remote Ischaemic Preconditioning in Transplantation (RIPTRANS) - A Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
496
Start Date
2019-03-12
Completion Date
2042-02
Last Updated
2020-03-10
Healthy Volunteers
No
Conditions
Interventions
RIPC
Remote Ischaemic Preconditioning
Sham-RIPC
Sham procedure
Locations (1)
Helsinki University Hospital
Helsinki, Finland