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Molecular Detection of Advanced Neoplasia in Pancreatic Cysts
Sponsor: Mayo Clinic
Summary
Researchers are trying to find out whether new tests ("biomarkers") of blood, stool, pancreas cyst fluid, or pancreas juice can be used to diagnose malignant or pre-malignant changes in pancreas cysts.
Official title: Molecular Detection of Advanced Neoplasia in Pancreatic Cysts (IN-CYST)
Key Details
Gender
All
Age Range
18 Years - 120 Years
Study Type
INTERVENTIONAL
Enrollment
800
Start Date
2018-05-11
Completion Date
2030-12-30
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Blood, stool, pancreatic juice and cyst fluid collection
Blood and stool will be collected at baseline from all study participants. Those in the Immediate Surgery group may undergo endoscopic pancreatic juice collection before surgery, either at the time of a clinically indicated endoscopic ultrasound (EUS) exam or during an optional pre-operative research endoscopy. Pancreatic cyst fluid will also be obtained from all participants in the Immediate Surgery group, either at the time of surgery, or during a clinically indicated preoperative EUS FNA procedure, or both. Pancreatic juice and cyst fluid will be collected opportunistically from participants in the Clinical Follow-up group who undergo a clinically indicated EUS, EUS FNA, or endoscopy exam.
Pancreatic Surgery
Surgical resection of pancreatic cyst
Endoscopy Exam
Clinically indicated endoscopic ultrasound
Locations (1)
Mayo Clinic
Rochester, Minnesota, United States