Clinical Research Directory

Inclusion Criteria: 1. Male or female patients aged 8 to 12 years (up to the day before the 13th birthday) 2. Myopia of -1 D to -6 D with reported or documented annual progression ≥ 0.5 D of myopia 3. Written informed consent obtained from patient (if applicable) and parents or legal guardians according to international guidelines and local laws 4. Ability to understand the nature of the trial and the trial related procedures and to comply with them Exclusion Criteria: 1. Asian or African origin 2. Abnormal binocularity 3. Strabismus 4. Astigmatism \>1.5 D 5. Anisometropia \>1.5 D 6. History of amblyopia 7. Corrected visual acuity in any eye \<0.63 8. Any acquired or developmental organic eye disease 9. Premature birth 10. Any known systemic metabolic disease or chromosomal anomaly 11. Previous use of any kind of contact lenses 12. Previous use of atropine eye drops 13. Epilepsy 14. Known hypersensitivity to the active substances or any of the excipients 15. Participation in any other interventional clinical trial within the last 30 days before the start of this trial 16. Simultaneous participation in other interventional trials which could interfere with this trial; simultaneous participation in registries and diagnostic trials is allowed 17. Contraindications according to the Summary of Product Characteristics (SmPC): Increased intraocular pressure (primary forms of glaucoma or narrow angle glaucoma), chronic rhinitis sicca 18. Caution and pediatric counselling shall be assured if any of the following conditions are present according to the Summary of Product Characteristics (SmPC): Cardiac insufficiency, arrhythmia, coronary stenosis, hyperthyroidism, stomach or bowel stenosis, bowel paralysis, megacolon, muscle weakness, lung edema, hypersensitivity to atropine, spastic paralysis 19. Parents or children with poor understanding of the German language 20. Person who is in a relationship of dependence/employment with the sponsor or the investigator