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Cerebral Cortical Influences on Autonomic Function
Sponsor: David Levinthal
Summary
This is an exploratory neurophysiological study that will determine the impact of non-invasive brain stimulation on autonomic regulation, with a focus on gastrointestinal function. These studies should provide a basis for future brain-based neurotherapeutic strategies in patients with functional GI disorders.
Key Details
Gender
All
Age Range
21 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
244
Start Date
2019-04-05
Completion Date
2026-10-03
Last Updated
2025-10-31
Healthy Volunteers
Yes
Interventions
rTMS
In subsequent sessions, the same measures of autonomic activity and MEPs will be monitored but different patterns of repetitive TMS (rTMS) will be applied to motor cortex or other areas before the test meal, water or nutrient drink is consumed.
Locations (1)
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States