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Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
Sponsor: Chinese University of Hong Kong
Summary
The study is aimed * To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery. * To test the hypothesis that Brown fat is an independent biomarker for the development of Non Alcoholic Fat Liver Disease (NAFLD) * To study the association among Brown fat, NAFLD and obesity.
Official title: Change of Adipose Tissues and Triglyceride in Obese Patients With Non-alcoholic Fatty Liver Disease After Bariatric Surgery or Life-style Intervention
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2019-04-01
Completion Date
2026-06-30
Last Updated
2025-02-13
Healthy Volunteers
No
Conditions
Interventions
Bariatric surgery
Use of the normal bariatric surgery procedures commonly conducted in our hospital, such as: Laparoscopic Roux-en-Y gastric bypass (RYGB) and Laparoscopic sleeve gastrectomy (LSG)
Dietitian led life style modification intervention
Intensive 6 months life style changes supervised by diatitians.
Conventional care (control)
receive routine care
Locations (1)
The Chinese University of Hong Kong, Prince of Wale Hospital
Hong Kong, Shatin, Hong Kong