Clinical Research Directory

Inclusion Criteria: SCAD Cases 1. Subjects of all ages, gender, or race 2. Subjects had coronary angiography. 3. Subjects had suspected SCAD as based on clinical report. Controls 1. INSPIRE subject that had coronary angiography at Intermountain Healthcare for stable angina. 2. Subjects had no or mild atherosclerotic heart disease at time of angiography. 3. Age at last visit as recorded in the Intermountain EDW at least 50 years or older. 4. Not screened as possibly having a SCAD or coronary artery dissection diagnosis. Exclusion Criteria: SCAD Cases 1. Independent review of cardiac imaging and clinical presentation by three cardiologists determine the coronary angiography was not a result of SCAD. 2. Imaging from time of coronary angiography of poor quality as to not allow for proper determination of SCAD. 3. Inability to determine criteria as outlined above. 4. Subjects that have had a heart transplant. 5. Subjects that have had a bone marrow transplant. 6. Inability or refusal of the patient and/or the patient's legally acceptable representative to provide informed consent or blood sample for any reason. 7. Other conditions that in the opinion of the Principal Investigator may increase risk to the subject and/or compromise the quality of the trial. Controls 1. Subjects that have a heart transplant. 2. Subjects that have a bone marrow transplant. 3. Subjects with any of the following diagnosis at anytime 1. Heart failure 2. Heart valve disease 3. Thoracic aortic aneurysm and dissection 4. Ehlers-Danlos syndrome 5. Shprintzen-Goldberg syndrome 6. Marfan syndrome 7. Loeys-Dietz aortic aneurysm syndrome 8. Arterial tortuosity syndrome