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Clinical Pre-screening Protocol for Ovarian Cancer
Sponsor: Allarity Therapeutics
Summary
The patient's local archival tumor tissue (FFPE) from original tumor, or from the metastatic tissue, will be collected to potentially identify if they - at a later stage of their disease - will be likely to benefit from treatment with any of the investigational cancer drugs available to Allarity Therapeutics. Data from this study can further be used to explore in a retrospective fashion, sensitivity to other chemotherapeutic drugs previously used in the treatment of their ovarian cancer, to investigate whether or not the DRP® method can predict and confirm the obtained sensitivity to the prior given drugs as well as prospective analyses guiding the Investigators on future treatments.
Official title: Development of Drug Response Predictor (DRP) to Test Sensitivity to Investigational Anti-Cancer Drugs in Patients With Advanced Ovarian Cancer
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2019-04-11
Completion Date
2026-12
Last Updated
2025-10-30
Healthy Volunteers
No
Conditions
Interventions
Drug Response Predictor® (DRP)
A DRP is an assay that based on samples from a tumor can predict whether the tumor will respond to a specific drug or not.
Locations (5)
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
OU Health Stephenson Cancer Center
Oklahoma City, Oklahoma, United States
Swedish Center for Research and Innovation
Seattle, Washington, United States
Beatson West of Scotland Cancer Centre
Glasgow, Scotland, United Kingdom
Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital
London, United Kingdom