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RECRUITING
NCT03877796

Clinical Pre-screening Protocol for Ovarian Cancer

Sponsor: Allarity Therapeutics

View on ClinicalTrials.gov

Summary

The patient's local archival tumor tissue (FFPE) from original tumor, or from the metastatic tissue, will be collected to potentially identify if they - at a later stage of their disease - will be likely to benefit from treatment with any of the investigational cancer drugs available to Allarity Therapeutics. Data from this study can further be used to explore in a retrospective fashion, sensitivity to other chemotherapeutic drugs previously used in the treatment of their ovarian cancer, to investigate whether or not the DRP® method can predict and confirm the obtained sensitivity to the prior given drugs as well as prospective analyses guiding the Investigators on future treatments.

Official title: Development of Drug Response Predictor (DRP) to Test Sensitivity to Investigational Anti-Cancer Drugs in Patients With Advanced Ovarian Cancer

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2019-04-11

Completion Date

2026-12

Last Updated

2025-10-30

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Drug Response Predictor® (DRP)

A DRP is an assay that based on samples from a tumor can predict whether the tumor will respond to a specific drug or not.

Locations (5)

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

OU Health Stephenson Cancer Center

Oklahoma City, Oklahoma, United States

Swedish Center for Research and Innovation

Seattle, Washington, United States

Beatson West of Scotland Cancer Centre

Glasgow, Scotland, United Kingdom

Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital

London, United Kingdom