Clinical Research Directory

Inclusion Criteria: * Age \>10 years to \<80 years * Neurologically intact spinal cord (with or without radiculopathy) * Undergoing primary or revision procedure in the spine * Anterior and/or posterior surgical approach for any of the following: * Correction of spinal deformity with a major Cobb angle of ≥ 80° in the coronal or sagittal plane * Correction of high grade spondylolisthesis (Grades 3- 5) * Posterior column or 3-column osteotomy * Requiring multimodal neuromonitoring with EMG, SSEP, and MEP as per standard of care * Informed consent obtained for patients i.e.: * Ability to understand the content of the patient information * Willingness and ability to participate in the clinical investigation according to the Clinical Investigation Plan (CIP) * Signed and dated EC/IRB approved written informed consent OR * Written consent obtained according to defined and IRB/EC approved procedures for patients who are not able to provide independent written informed consent Exclusion Criteria: • Neurodegenerative disease * Upper motor neuron lesion * Growing rods or growth guidance procedures * Tether or staple procedures * Stand-alone cervical deformity correction procedures * Any not medically managed severe systemic disease * Recent history of substance abuse (ie recreational drugs, alcohol) that would preclude reliable assessment * Pregnancy or women planning to conceive within the study period * Prisoner * Participation in any other medical device or medicinal product study that could influence the results of the present study