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PRISM Intervention Study
Sponsor: University of California, Los Angeles
Summary
This research study, Personalized, Responsive Intervention Sequences for Minimally Verbal Children with Autism (PRISM), is designed to maximize language outcomes for limited-language preschoolers, thereby lowering the risk of being classified as "minimally verbal" at age 6, by empirically developing a two-stage, 20-week adaptive intervention approach in a real world community settings. If found efficacious, the adaptive intervention design will capitalize on the heterogeneity and evolving status of children with ASD by providing the best intervention (DTT, JASPER and CET) for children who need it (leading to individualized sequences of intervention), only when it is needed (potentially reducing burden on children).
Official title: Personalized, Responsive Intervention Sequences for Minimally Verbal Children With Autism
Key Details
Gender
All
Age Range
36 Months - 59 Months
Study Type
INTERVENTIONAL
Enrollment
140
Start Date
2021-03-01
Completion Date
2026-07-31
Last Updated
2026-03-18
Healthy Volunteers
No
Conditions
Interventions
JASPER
JASPER is a developmentally anchored behavioral intervention that assumes that communication develops from social interactions in which specific social engagement strategies, symbolic representations, and early communication forms are modeled and naturally reinforced by the adult's responses to the child.
DTT (Discrete Trial Training)
DTT is an adult-led, highly structured, behavioral teaching approach, is considered to have the strongest evidence as a "standard of care" for young children with autism. DTT emphasizes didactic, adult-led instruction.
Locations (3)
UCLA
Los Angeles, California, United States
University of Rochester
Rochester, New York, United States
University of Oregon
Eugene, Oregon, United States