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Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)
Sponsor: University of Virginia
Summary
The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and muscle capillary blood volume, improves vascular function in the larger conduit vessels, and enhances insulin's metabolic action in humans with Type 2 diabetes. Subjects will be randomized to one of the three groups: exercise training, liraglutide treatment, and exercise + liraglutide. They will be studied at the baseline and then after 16 weeks of intervention.
Key Details
Gender
All
Age Range
21 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2019-02-28
Completion Date
2027-12
Last Updated
2026-08-12
Healthy Volunteers
Yes
Conditions
Interventions
Exercise
16 weeks of treatment
Liraglutide
16 weeks of Liraglutide
Locations (1)
University of Virginia
Charlottesville, Virginia, United States