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Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures
Sponsor: C. Liam Dwyer
Summary
The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures. The investigators hypothesize that patients who receive GC will have improved ROM and functional outcome measures compared to patients who do not receive GC. In addition, this study aims to determine if there is a difference in rates of complications and postoperative pain control between the GC and non-GC groups. In order to accomplish these aims, the investigators will conduct a prospective, randomized, controlled investigation.
Official title: The Effect on Wrist Range of Motion With Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2019-07-10
Completion Date
2024-12
Last Updated
2024-05-01
Healthy Volunteers
No
Conditions
Interventions
Dexamethasone
Intraoperative: Single intraoperative dose of 10 mg intravenous dexamethasone
Methylprednisolone
Postoperative: A 6-day oral methylprednisolone (oral GC) taper course. The oral GC taper course begins on the day of surgery and includes 24mg on day 1, 20mg on day 2, 16mg on day 3, 12mg on day 4, 8mg on day 5, and 4mg on day 6
Locations (1)
Geisinger Woodbine
Danville, Pennsylvania, United States