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French Registry for Monitoring Pregnancies for Multiple Sclerosis
Sponsor: Hospices Civils de Lyon
Summary
The influence of pregnancy on the course of multiple sclerosis (MS) has long been a controversial topic. After the publication of the first large prospective study of pregnancy and MS in 1998, counselling of women with MS has radically changed and many patients have been able to fulfill their desire of motherhood. However, there are still some challenges for the neurologist, who has to face old unanswered questions or new issues, regarding the use of disease modifying drugs (DMDs) in this period of life, effects on the short and long term outcome of the mother (in terms of relapses and disability) and the child, role of breast-feeding and locoregional analgesia. To set up a national prospective pregnancy registry for patients with MS, nested within the Observatoire Français de la Sclérose en Plaque (OFSEP) cohort, owing to a better knowledge of interactions between MS and pregnancy-related issues (pregnancy itself, locoregional analgesia, breastfeeding, impact of using or stopping DMDs on women/children…)
Official title: French Registry for Monitoring Pregnancies and Children of Women With Multiple Sclerosis Within The Observatoire Français de la Sclérose en Plaque (OFSEP) Cohort
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
1500
Start Date
2019-08-12
Completion Date
2036-08-12
Last Updated
2026-01-05
Healthy Volunteers
No
Conditions
Interventions
No intervention
No intervention
Locations (48)
Chu D'Amiens
Amiens, France
Centre Hospitalier Annecy Genevois
Annecy, France
Centre Hospitalier d'Avignon
Avignon, France
Hopital Jean Minjoz
Besançon, France
Hopital Pellegrin
Bordeaux, France
Hôpital de Brive
Brive-la-Gaillarde, France
Hôpital Neurologique Pierre Wertheimer
Bron, France
Hopital Cote de Nacre
Caen, France
Centre hospitalier Métropole Savoie
Chambéry, France
Hopital Gabriel Montpied
Clermont-Ferrand, France
Hopital Henri Mondor
Créteil, France
Hopital Du Bocage
Dijon, France
Ch Epinal
Épinal, France
Hôpital Raymond Poincaré
Garches, France
Centre hospitalier Joséphine Baker Gonesse
Gonesse, France
Chu de Grenoble
Grenoble, France
Centre Hospitalier de Versailles Hôpital Andre Mignot
Le Chesnay, France
Hôpital St Vincent De Paul
Lille, France
Chru de Lille
Lille, France
Hopital Dupuytren
Limoges, France
Cabinet médical Dr Philippe NEUSCHWANDER
Lyon, France
Centre Hospitalier Saint Joseph Saint Luc
Lyon, France
Cabinet médical Dr C. CORNUT-CHAUVINC
Lyon, France
Hopital Timone Adultes
Marseille, France
Hopital Gui de Chauliac
Montpellier, France
Cabinet médical Dr L. GUILLOTON
Mornant, France
Hôpital Central
Nancy, France
Hopital Pasteur
Nice, France
Hopital Caremeau
Nîmes, France
Hôpital Paris Saint Joseph
Paris, France
Fondation Rotschild
Paris, France
Hôpital national des Quinze-Vingt.
Paris, France
Hopital Pitie Salpetriere
Paris, France
Chi Poissy Saint Germain En Laye
Poissy, France
Chr La Miletrie
Poitiers, France
Hopital Rene Dubos
Pontoise, France
Hopital Pontchaillou
Rennes, France
Hôpital Charles-Nicolle
Rouen, France
Centre Hospitalier de Saint-Denis
Saint-Denis, France
Hopital G. Et R. Laennec
Saint-Herblain, France
Centre Hospitalier Mémorial
Saint-Lô, France
Hopital Nord
Saint-Priest-en-Jarez, France
Hopital Hautepierre
Strasbourg, France
Hôpital Foch
Suresnes, France
Hopital Purpan
Toulouse, France
Chru de Tours Hopital Bretonneau
Tours, France
Médipôle Lyon Villeurbanne
Villeurbanne, France
Hopital P. Zobda-Quitman
Fort-de-France, Martinique