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Quantitative Dual Energy Computed Tomography in Pulmonary Hypertension
Sponsor: University Hospital, Bordeaux
Summary
Pathophysiological mechanisms leading to pulmonary hypertension (PH) are complex. Quantitative computed tomography (QCT) can help us to study morphological alterations in patients with PH. These CT morphometrics are useful to predict the degree of PH severity at least in PH secondary to chronic obstructive pulmonary disease (COPD). We hypothesized that assessing lung perfusion using dual energy CT (DECT) can refine our knowledge on PH pathophysiology and help to predict PH severity irrespective of its etiology
Official title: Quantitative Dual Energy Computed Tomography in Pulmonary Hypertension "DECTPH".
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2019-08-02
Completion Date
2021-01-15
Last Updated
2026-05-29
Healthy Volunteers
No
Conditions
Interventions
dual energy CT scans
The procedure involves post processing and analysis of reconstructed images from dual energy CT scans available at the Bordeaux University Hospital and used in routine care, which will allow us to collect morphometric data (bronchial wall thickness and cross sectional area of small pulmonary vessels) and to assess pulmonary perfusion by studying iodine mapping and quantifying pulmonary perfusion blood volume (PVB)
Locations (1)
CHU Bordeaux
Bordeaux, France