Clinical Research Directory
Browse clinical research sites, groups, and studies.
Identification of microRNAs Involved in Cerebral Collateral Regulation
Sponsor: Virginia Commonwealth University
Summary
Patients \>18 years of age presenting to Ohio State Wexner Medical Center Emergency department with stroke symptoms, within 6 hours of last know well and found to have acute anterior circulation large vessel occlusion (LVO) will be included in this study. The purpose of this study is to evaluate the differential expression of exosomal microRNAs in patients with stroke due to acute LVO as compared to healthy controls. In addition, the investigators will also evaluate the differential expression of exosomal microRNA in patients with good vs poor collateral grade.
Official title: Evaluation of Circulating Exosomal MicroRNAs as Surrogate Stroke-Clock in Acute Anterior Circulation Large Vessel Occlusion
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
45
Start Date
2018-08-14
Completion Date
2027-12-01
Last Updated
2026-08-17
Healthy Volunteers
Yes
Conditions
Interventions
miRNA sampling
Blood samples for miRNA testing will be collected from all subjects (control and patients diagnosed with acute ischemic stroke)
Locations (2)
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
Virginia Commonwealth University
Richmond, Virginia, United States