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Effects of a Probiotic in Hypertension
Sponsor: Charite University, Berlin, Germany
Summary
High blood pressure is a major risk factor for cardiovascular events, including stroke, heart and kidney failure. Typical anti-hypertensive drugs target vessels, the kidneys or the heart. Here we propose a randomized, placebo-controlled study to test the blood pressure-lowering effect of a probiotic in 110 patients with grade 1 hypertension. In addition, we will investigate glucose variability, fecal bacterial metabolome, peripheral blood effector T cell frequencies (%) and health-related quality of life.
Official title: Effect of a Probiotic on Blood Pressure in Low-to-moderate Risk Grade 1 Hypertension - a Randomized Study
Key Details
Gender
All
Age Range
50 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2019-09-02
Completion Date
2025-09-01
Last Updated
2024-07-09
Healthy Volunteers
No
Conditions
Interventions
Vivomixx®
Microbiotic food supplement with L. paracasei, L. plantarum, L. acidophilus, L. delbrueckii, B. longum, B. infantis, B. breve, S. thermophilus
Placebo
Placebo with similar appearance to probiotic
Locations (1)
Experimental and Clinical Research Center
Berlin, Germany