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Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation
Sponsor: Spaulding Rehabilitation Hospital
Summary
The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury. The goal is to provide the same level of pain relief with a reduced opioid dose to diminish adverse effects as well as the risk of addiction associated with narcotic treatment.
Official title: Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Patients With Spinal Cord Injury, Polytrauma and Burn Injury: A Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2019-02-20
Completion Date
2021-11-01
Last Updated
2026-08-04
Healthy Volunteers
No
Interventions
Placebo
Sugar pill used to condition patients.
Oxycodone
An opioid used for analgesia.
Essential Oil
An aromatic oil used for conditioning.
Locations (1)
Spaulding Rehabilitation Hospital
Charlestown, Massachusetts, United States