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COMPLETED
NCT03906721
PHASE2

Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation

Sponsor: Spaulding Rehabilitation Hospital

View on ClinicalTrials.gov

Summary

The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury. The goal is to provide the same level of pain relief with a reduced opioid dose to diminish adverse effects as well as the risk of addiction associated with narcotic treatment.

Official title: Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Patients With Spinal Cord Injury, Polytrauma and Burn Injury: A Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2019-02-20

Completion Date

2021-11-01

Last Updated

2026-08-04

Healthy Volunteers

No

Interventions

DRUG

Placebo

Sugar pill used to condition patients.

DRUG

Oxycodone

An opioid used for analgesia.

OTHER

Essential Oil

An aromatic oil used for conditioning.

Locations (1)

Spaulding Rehabilitation Hospital

Charlestown, Massachusetts, United States