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NCT03907631

Multi-centre Acute Severe Ulcerative Colitis Prospective Cohort Study (Elevate ASUC)

Sponsor: Hull University Teaching Hospitals NHS Trust

View on ClinicalTrials.gov

Summary

Up to one third of patients with Ulcerative Colitis (UC) will require hospitalisation for severe disease (ASUC - Acute Severe Ulcerative Colitis), often within the first 12 months of diagnosis. 30-40% of people admitted to hospital with ASUC will require colectomy during the emergency admission. Investigators will develop a multi-centre prospective inception cohort of patients with ASUC with homogeneously collected detailed longitudinal clinical, endoscopic and laboratory data.

Official title: Elevate ASUC - Evaluating Clinical and Endoscopic Variables in Assessment, Treatment and Outcome Endpoints in Acute Severe Ulcerative Colitis

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

189

Start Date

2019-10-18

Completion Date

2026-08-31

Last Updated

2026-02-17

Healthy Volunteers

No

Interventions

OTHER

Standard of care

care decisions driven by local physicians; this is an observational cohort

Locations (1)

Gastroenterology, Hull Royal Infirmary, Hull University Teaaching Hospitals NHS Trust

Hull, United Kingdom