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Multi-centre Acute Severe Ulcerative Colitis Prospective Cohort Study (Elevate ASUC)
Sponsor: Hull University Teaching Hospitals NHS Trust
Summary
Up to one third of patients with Ulcerative Colitis (UC) will require hospitalisation for severe disease (ASUC - Acute Severe Ulcerative Colitis), often within the first 12 months of diagnosis. 30-40% of people admitted to hospital with ASUC will require colectomy during the emergency admission. Investigators will develop a multi-centre prospective inception cohort of patients with ASUC with homogeneously collected detailed longitudinal clinical, endoscopic and laboratory data.
Official title: Elevate ASUC - Evaluating Clinical and Endoscopic Variables in Assessment, Treatment and Outcome Endpoints in Acute Severe Ulcerative Colitis
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
189
Start Date
2019-10-18
Completion Date
2026-08-31
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Standard of care
care decisions driven by local physicians; this is an observational cohort
Locations (1)
Gastroenterology, Hull Royal Infirmary, Hull University Teaaching Hospitals NHS Trust
Hull, United Kingdom