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Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF
Sponsor: Third Affiliated Hospital, Sun Yat-Sen University
Summary
This study is to investigate the clinical efficacy of three types of nucleotide/nucleoside analogues in treatment of HBV-related acute-on-chronic liver failure.
Official title: Study on Three Types of Nucleotide/Nucleoside Analogues Treatment in Patients With Hepatitis b Virus Related Acute-on-chronic Liver Failure
Key Details
Gender
All
Age Range
12 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2019-02-21
Completion Date
2024-12-31
Last Updated
2024-11-29
Healthy Volunteers
No
Interventions
Entecavir
Patients would receive treatment of oral entecavir (ETV) 0.5 mg once per day.
Tenofovir Disoproxil Fumarate
Patients would receive treatment of oral tenofovir disoproxil fumarate (TDF) 300 mg once per day.
Tenofovir Alafenamide
Patients would receive treatment of oral tenofovir alafenamide (TAF) 25 mg once per day.
Locations (1)
Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China