Clinical Research Directory

Inclusion Criteria: 1. TNM stage I-II (T1-4N0M0) colorectal cancer cases 2. receive radical surgical resection 3. have completed data of tumor location, histological type, behavioral characteristics or TNM staging 4. have tumor specimens and either a valid microsatellite instability (MSI) or immuno-histochemistry (IHC) data 5. have valid V-raf murine sarcoma viral oncogene homolog B1 (BRAF), kirsten rat sarcoma viral oncogene (KRAS), CpG island methylator phenotype (CIMP) results 6. have at least 4 years of follow-up 7. have valid time to local recurrence/metastasis in follow-up 8. have clinical/treatment record data and valid preoperative status of intestinal obstruction or perforation (IOP), counts of lymph node removed in surgical resection. Exclusion Criteria: 1. have had a previous diagnosis of any cancer or presence of any tumor other than the CRC 2. have had inflammatory bowel disease 3. have had hereditary colorectal cancer syndromes, including Familial adenomatous polyposis, mutyh (MYH)-associated polyposis, Peutz-Jeghers syndrome, Juvenile polyposis coli, phosphate and tension homology deleted on chromosome ten (PTEN) tumor-hamartoma syndromes, Lynch Syndrome, and Familial Colorectal Cancer Type X.