Clinical Research Directory

Inclusion Criteria: * Patient with a diagnosis of advanced cancer (metastatic or recurrent incurable solid tumors) * Presence of fatigue of \>= 4/10 on Edmonton Symptom Assessment System (ESAS) Fatigue item (0-10 severity scale) * Patient should describe fatigue as being present for a minimum of 2 weeks prior to screening * Uncontrolled pain; patient is on opioids for the treatment of cancer pain, he/she must have had no major dose change (\> 25%) for at least 48 hours prior to study entry. Change in opioid dose after study entry is allowed * Patient must be 18 years of age or older. The questionnaires used in this study have been validated only in the adult population * Patient must be willing to engage in telephone follow up with research staff * Patient must have telephone access to be contacted by the research staff * Hemoglobin level of \>= 8 g/dL. Patient may receive packed red blood cell (PRBC) transfusion so as to have hemoglobin level of \>= 8 g/dL so at participate in the study Exclusion Criteria: * Surgery, or pain relieving procedures within 2 weeks of entry into the study or during the study period * Patients with history of substance abuse (Cut down, Annoyed, Guilty, Eye opener \[CAGE\] \>= 2+), cognitively impaired (MD Anderson Symptom \[MDAS\] \> 7)