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RECRUITING
NCT03929887

KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis

Sponsor: Seoul National University Hospital

View on ClinicalTrials.gov

Summary

Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis is uncertain. Recently, along with advances in molecular analysis and computational bioinformatics, genomic data from human renal biopsies could provide a strong foundation for the future of precision medicine in nephrology. In response to a request for applications by the Ministry of Health and Welfare of Korea for the creation of Clinical Research Registry, multi-center N network has been established for prospective cohort with kidney biopsy samples (KORNERSTONE). Through this Network the investigators hope to understand the fundamental biology of glomerulonephritis and aim to bank long-term observational data and corresponding biological data including genomic data from kidney tissues, and kidney pathologic data which is digitalized This database is archived to a web-based platform to access easily and further enrich for researchers.

Official title: Multicenter Prospective Cohort of Kidney Biopsy for Glomerular Disease Research

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

3000

Start Date

2019-05-01

Completion Date

2028-12-31

Last Updated

2020-02-12

Healthy Volunteers

No

Interventions

OTHER

Kidney Biopsy

Patients scheduled to undergo a clinically indicated kidney biopsy will be requested to consent to an additional renal core and various patient-derived samples.

Locations (6)

KangWon National University Hospital

Chuncheon, South Korea

Keimyung University Dongsan Medical Center

Daegu, South Korea

Chung-Ang University Hosptial

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Severance Hospital

Seoul, South Korea

SMG-SNU Boramae Medical Center

Seoul, South Korea