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RECRUITING
NCT03935139
NA

Monitoring of the Bone Free Flaps With Microdialysis

Sponsor: Centre Hospitalier Universitaire, Amiens

View on ClinicalTrials.gov

Summary

Microdialysis is admitted to be reliable by numerous surgeons to monitor flaps. Nevertheless, a few authors reported follow up with microdialysis in bone free flaps, and they all describe the position of the catheter in the surrounding soft tissue muscle which is not the accurate reflect of bone vascularisation. The aim of this study is to determine the lactate/pyruvate ratio mean value in bone free flaps with a microdialysis catheter directly positioned in the bone tissue.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2019-07-22

Completion Date

2025-07

Last Updated

2024-07-10

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

glucose measurement

Glucose values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.

BIOLOGICAL

lactacte measurement

Lactate values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.

BIOLOGICAL

pyruvate measurement

pyruvate values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.

BIOLOGICAL

glycerol measurement

glycerol values will be recorded during 5 days as following : every hour at day 0, every 2 hours at day 1, every 3 hours at days 2 to 5.

PROCEDURE

Bone free flap monitoring

Bone free flaps will be monitored with a microdialysis catheter directly positioned in bone tissue.

Locations (1)

CHU Amiens

Amiens, France