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A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
This study proposes to use a new instrument (AO-OCT/AF: adaptive optics - optical coherence tomography/autofluorescence) combined with a data processing method to image the retinal pigment epithelium (RPE) of the eye in normal subjects and in subjects with age-related macular degeneration. (AMD). While currently there is no cure, with early diagnosis, vision loss can be slowed. The technology being developed for this project will be the first imaging modality that can provide both structural and molecular information about the retina in vivo and in 3D.
Official title: Snapshot 3D Ultra-high-resolution OCT and Hyperspectral AF of In-vivo Retina
Key Details
Gender
All
Age Range
60 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2023-09-06
Completion Date
2027-12
Last Updated
2026-02-24
Healthy Volunteers
Yes
Conditions
Interventions
adaptive optics AO-OCT/AF instrument
Using the new adaptive optics AO-OCT/AF instrument, the study team will image 10 normal subjects in order to optimize image acquisition and interpretation.
adaptive optics AO-OCT/AF instrument
Using the new adaptive optics AO-OCT/AF instrument, the study team will image 40 adult subjects with age-related macular degeneration (AMD) who have non-neovascular AMD and soft drusen or subretinal drusenoid deposits in the macula.
Locations (1)
New York Eye and Ear Infirmary of Mount Sinai
New York, New York, United States