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Impact of Dietary Fiber as Prebiotics on Intestinal Microbiota in Obese Thai Children
Sponsor: Chulalongkorn University
Summary
This study evaluates the changes in gut microbiota composition, body fat, children's eating behaviors, plasma amino acids, and satiety hormones (Peptide-YY and GLP-1) after a 6-month period in obese Thai children. A total of 165 children, aged 7 to 15 years with a Body Mass Index (BMI) ≥ median + 2 standard deviation (SD), were randomized into three groups: Group A (intervention group) received inulin daily. Group B received an isocaloric maltodextrin placebo. Group C received dietary fiber advice aimed to match age-appropriate recommendations.
Key Details
Gender
All
Age Range
7 Years - 15 Years
Study Type
INTERVENTIONAL
Enrollment
165
Start Date
2017-08-01
Completion Date
2020-07-09
Last Updated
2026-07-02
Healthy Volunteers
No
Conditions
Interventions
Inulin
The intervention group (group A) consumed 10 g of inulin extracted from Thai Jerusalem artichoke by our patent technique (Patent no. 15858) administered once daily before dinner. The placebo group (group B) received isocaloric maltodextrin, while the dietary fiber advice group (group C) received guidance based on age-appropriate intake recommendations.
Locations (1)
Chulalongkorn University
Bangkok, Thailand