Clinical Research Directory

Inclusion Criteria: * Voluntarily participate in the trial and provide the informed consent form; * Male or female patients aged ≥ 18 years; * Planned to undergo elective on-pump valve surgery due to primary mitral and/or aortic valvular heart disease (such as rheumatic, degenerative, infective, congenital valvular heart disease, etc.); * At least one target coronary arteries (anterior descending branch, circumflex branch, main right coronary artery or its primary branches with ≥ 1.5 mm in diameter, such as diagonal branch, intermediate branch, obtuse marginal branch, posterior descending branch and posterior branch of left ventricle) with preoperative diameter stenosis of ≥ 50% by coronary angiography (visual estimation, subject to written coronary angiography report) and suited for CABG revascularization. Exclusion Criteria: * History of heart surgery; * Planned second-stage PCI or CABG revascularization; * Secondary valvular heart disease (ischemia, cardiomyopathy); * Planned valve intervention surgery through the catheter; * Subjects that were evaluated to have cardiogenic shock or other critical conditions that were not appropriate for the trial by study physician; * QFR calculations cannot be carried out from preoperative coronary angiography data (such as poor projection position, inability to detect vascular boundaries, poor contrast agent filling, excessive overlap or severely distorted of vessel lesion sections, lesion involved in myocardial bridge, or lesion site within 3 mm from the ostium of the main coronary artery); * The target coronary arteries were evaluated to be not suitable for CABG by study physician; * Life expectancy \< 3 years.