Clinical Research Directory

Inclusion Criteria: * presence of at least one screw-type titanium implant exhibiting bleeding and/or suppuration on probing combined with: 1. PPD ≥ 5 mm and bone loss ≥ 2 mm (compared to crestal bone levels at the time of placement of the reconstruction) 2. PPD ≥6 and bone loss ≥3 (not compared to crestal bone levels at the time of placement of the reconstruction) * single tooth and bridgework restorations without overhangs no evidence of occlusal overload (i.e. occlusal contacts revealed appropriate adjustment) * treated chronic periodontitis and proper periodontal maintenance care FMPS \< 20% * non-smoker or light smoking status in smokers (\<10 cigarettes per day) implant function time ≥ 1 year. Exclusion Criteria: * Patients with uncontrolled diabetes * patients with osteoporosis or under bisphosphonate medication, * pregnant or lactating women * patients with a history of radiotherapy to the head and neck region hollow implants * implant mobility * implants at which no position could be identified where proper probing measurements could be performed; * previous surgical treatment of the peri-implantitis lesions