Clinical Research Directory

Inclusion Criteria: * Age ≥65 years; * Can get up from a chair and walk 6 meters * Clearly consciousness, able to read or use words to express and communicate without difficulty * Agree and accept the study plan Exclusion Criteria: * Acute and chronic inflammatory disease of the intestine within 3 months * Use of antibiotics, probiotics, prebiotics or synthetics, laxatives or diarrhea medications, proton pump inhibitors or gastric motility drugs within 1 month * Dementia * mental illness or blindness * acute infection * cancer