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RECRUITING
NCT03997253
NA

Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management

Sponsor: University Hospital, Limoges

View on ClinicalTrials.gov

Summary

Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs. Despite undeniable success in the short term, due to major advances in surgery, medicine and research, transplant recipients continue to face the risk of chronic rejection and long-term complications. The University Hospital Federation "FHU SUPORT" was created to optimize the chances of success of the organ transplant and improve the quality of life of the transplanted patient. FHU SUPORT 's ambition is based on a translational strategy that presents two priority areas: Axis 1: Optimization, evaluation, conditioning of the donor, graft, recipient Axis 2: Personalized follow-up of the transplanted patient in the short and long term Identifying factors for long-term graft and patient survival through translational research from a common cohort and biological collection will predict transplant rejection, prolong graft function, or improve the patient's care.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

430

Start Date

2020-12-21

Completion Date

2027-06

Last Updated

2026-06-29

Healthy Volunteers

No

Interventions

OTHER

blood and urine samples

various blood and urine samples will be collected from the recipient at D0, D7, D14, M1, M3, M6 and M12 and intraoperative bile collection

Locations (4)

Limoges hospital

Limoges, France

Poitiers Hospital

Poitiers, France

Rennes Hospital

Rennes, France

Tours hospital

Tours, France