Clinical Research Directory
Browse clinical research sites, groups, and studies.
Non-Invasive Spinal Cord Stimulation After Injury
Sponsor: University of Louisville
Summary
The goal of this study is to assess the function of the lungs and the muscles are used to breathe after individuals receive respiratory training, spinal cord stimulation, a combination of respiratory training and stimulation, a combination of arm training and stimulation, or a combination of trunk training and stimulation. The respiratory, arm, and trunk training combined with the spinal stimulation interventions are being used to activate the spinal cord below the level of injury. Investigators will be looking for changes in the function of the lungs and trunk muscles before, during, and after these task-specific and non-task-specific interventions for breathing to determine which one has the greatest effect. The results of this study may aid in the development of treatments to help individuals with spinal cord injuries that have impaired lung, arm, and trunk function.
Official title: Non-Invasive Spinal Cord Stimulation and Respiratory Plasticity
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2018-05-17
Completion Date
2029-12-31
Last Updated
2026-03-13
Healthy Volunteers
Yes
Conditions
Interventions
Transcutaneous Electrical Spinal Cord Stimulation (TcESCS)
TcESCS is a non-invasive DC battery powered device. Investigators and/or research team members will continually assess the appropriate stimulation parameters including configurations, current, voltage and frequency delivered by up to five active electrodes applied on skin of the back from cervical to lumbar levels. Stimulation parameters used during experimental assessments and interventions will be closely monitored by the research team. Every research participant will be slowly acclimated to stimulation. Blood pressure, heart rate, respiratory rate, and electromyography will be closely monitored while we are determining the correct stimulation parameters in the lab. During the stimulation training sessions, we will monitor blood pressure regularly throughout the session.
Locations (1)
Frazier Rehabilitation and Neuroscience Institute
Louisville, Kentucky, United States