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Imaging of Neuro-Inflammation and the Risk for Post-Traumatic Epilepsy
Sponsor: University of California, Davis
Summary
This study plans to evaluate the time course of inflammation in the brain after a moderate to severe traumatic brain injury using positron emission tomography (PET) brain imaging. Patients will undergo PET scans of the brain at two weeks and two months after injury to measure neuro-inflammation. The results of the PET scans will be analyzed and correlated with the risk of post-traumatic epilepsy.
Official title: Imaging of Glial Activation and Risk for Post-Traumatic Epilepsy
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2020-02-01
Completion Date
2026-08-14
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
[18F]DPA-714 Positron Emission Tomography Scan
All patients will undergo a \[18F\]DPA-714 PET scan of the brain 2 weeks and 2 months following moderate to severe traumatic brain injury to quantify neuroinflammation.
Locations (1)
University of California, Davis
Sacramento, California, United States