Clinical Research Directory

Inclusion Criteria: * Age 50 years or older * Resident of the continental United States * Diagnosed with multiple myeloma, non-Hodgkin lymphoma, or localized kidney or ovarian cancer; or \[localized (includes in situ) through regional\] breast, colorectum, endometrium, thyroid, or prostate cancer. * Completed primary treatment (surgery, radiation or chemotherapy). Active surveillance among men with prostate cancer or women with ductal carcinoma in situ is acceptable. * Completion of the 8th grade of school. Able to read and write English. * Normal blood pressure or those with high blood pressure for whom physician permission was granted. * Community dwelling. * Reside in an area that receives wireless coverage. * Have an active email address or be willing to have one created for the study. * Current body mass index of greater than or equal to 25 kg/m2, but less than 50 kg/m2. * Current physical activity level is less than 150 minutes of moderate-to-vigorous exercise per week. Exclusion Criteria: * Participation in another diet and exercise program. * Evidence of progressive cancer of the eligible types. * Recurrence of the eligible cancer types (exceptions are biochemical recurrence of prostate cancer). * A physician has provided instruction to limit current physical activity. * Pre-existing medical conditions that preclude adherence to an unsupervised weight loss intervention (e.g., pregnancy, severe orthopedic conditions, impending hip or knee replacement (within 6 months), end-stage renal disease, paralysis, dementia, blindness, unstable angina, untreated stage 3 hypertension, or recent history of heart attack, congestive heart failure or pulmonary conditions that required oxygen or hospitalization within 6 months). * Second primary cancers, with the exception of non-melanoma skin cancer, or if the initial and second cancers are both deemed eligible cancers. * Reside in a skilled nursing or assisted living facility.