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Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
Sponsor: The University of Texas Health Science Center, Houston
Summary
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
5000
Start Date
2016-06-15
Completion Date
2037-01-01
Last Updated
2026-02-02
Healthy Volunteers
Yes
Locations (20)
HOAG memorial hospital presbyterian
Newport Beach, California, United States
Hoag Memorial Hospital Presbyterian
Newport Beach, California, United States
Sutter Health
Sacramento, California, United States
University of Kentucky
Lexington, Kentucky, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
University of Michigan
Ann Arbor, Michigan, United States
Washington University in St. Louis
St Louis, Missouri, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
St. Francis Hospital (Catholic Health)
Roslyn, New York, United States
Oregon Health & Science University
Portland, Oregon, United States
Baylor College of Medicine
Houston, Texas, United States
Texas Children's Hospital
Houston, Texas, United States
The University of Texas Health Science Center at Houston
Houston, Texas, United States
Inova Health System
Falls Church, Virginia, United States
University of Sydney
Sydney, New South Wales, Australia
Ghent University Hospital (UZ Gent)
Ghent, East Flanders, Belgium
Foothills Medical Centre / Alberta Health Services
Calgary, Alberta, Canada
Toronto General Hospital (UHN)
Toronto, Ontario, Canada
Hospital Universitari Vall d'Hebron
Barcelona, Catalonia, Spain
Great Ormond Street Hospital
London, England, United Kingdom