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Haemochromatosis and Periodontitis
Sponsor: Rennes University Hospital
Summary
Periodontitis is a chronic inflammatory disease that affects tissues surrounding the teeth. It is strongly associated with the major pathogenic "red complex", including Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola1 and thus is considered an infection. Recent advances in the pathogenesis of periodontal disease have suggested that polymicrobial synergy and microbiota dysbiosis together with a dysregulated immune response can induce inflammation-mediated damage in periodontal tissues2-4. Interestingly, currently periodontitis is associated with a growing number of systemic diseases, including cardiovascular diseases, adverse pregnancy outcomes, diabetes5-7 and hereditary haemochromatosis8.
Key Details
Gender
All
Age Range
35 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
87
Start Date
2010-06-06
Completion Date
2011-12-01
Last Updated
2026-06-12
Healthy Volunteers
No
Conditions
Interventions
dental probes
Measurement of the depth of the periodontal pockets and clinical loss
Locations (1)
Rennes University Hospital
Rennes, France